Medicine Listing (Dec 2020)

1. AF 400 Tablet

Prescription Required

MANUFACTURER: Systopic Laboratories Pvt Ltd

SALT COMPOSITION: Fluconazole (400mg)

INTRODUCTION

AF 400 Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.

SIDE EFFECTS OF AF TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of AF
- Headache
- Nausea
- Stomach pain

Ref: 1mg

Salt Information:

Fluconazole is an antifungal medication used for a number of fungal infections. This includes candidiasis, blastomycosis, coccidiodomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis versicolor. It is also used to prevent candidiasis in those who are at high risk such as following organ transplantation, low birth weight babies, and those with low blood neutrophil counts. It is given either by mouth or by injection into a vein.

Common side effects include vomiting, diarrhea, rash, and increased liver enzymes. Serious side effects may include liver problems, QT prolongation, and seizures. During pregnancy it may increase the risk of miscarriage while large doses may cause birth defects. Fluconazole is in the azole antifungal family of medication. It is believed to work by affecting the fungal cellular membrane.

Fluconazole was patented in 1981 and came into commercial use in 1988. It is on the World Health Organization's List of Essential Medicines. Fluconazole is available as a generic medication. In 2017, it was the 182nd most commonly prescribed medication in the United States, with more than three million prescriptions.

Ref: Wikipedia

2. Sertaconazole (in the form of Sertaconazole Nitrate cream) 

Sertaconazole, sold under the brand name Ertaczo among others, is an antifungal medication of the imidazole class. It is available as a cream to treat skin infections such as athlete's foot.

It is also available in a vaginal tablet form. The most popular of these is Gyno-Dermofix.[citation needed]

Sertaconazole has several known mechanisms of action. It is considered fungistatic, fungicidal, antibacterial, antiinflammatory, antitrichomonal, and antipruritic.

Side effects:

Side effects were rarely reported with sertaconazole therapy, but may include contact dermatitis, burning on application site and skin dryness.

Ref:
% Wikipedia - Sertaconazole

% Wikipedia - Antifungal

3. Beclomethasone Dipropionate (in the form of topical cream) 

Following information is about the 'Beclometasone' chemical compound.

Beclometasone, also known as beclometasone dipropionate, and sold under the brand name Qvar among others, is a steroid medication. It is available as an inhaler, cream, pills, and nasal spray. The inhaled form is used in the long-term management of asthma. The cream may be used for dermatitis and psoriasis. The pills have been used to treat ulcerative colitis. The nasal spray is used to treat allergic rhinitis and nasal polyps.

Common side effects with the inhaled form include respiratory infections, headaches, and throat inflammation. Serious side effects include an increased risk of infection, cataracts, Cushing's syndrome, and severe allergic reactions. Long-term use of the pill form may cause adrenal insufficiency. The pills may also cause mood or personality changes. The inhaled form is generally regarded as safe in pregnancy. Beclometasone is mainly a glucocorticoid.

Beclometasone dipropionate was first patented in 1962 and used medically in 1972. It was approved for medical use in the United States in 1976. It is on the World Health Organization's List of Essential Medicines. In 2017, it was the 153rd most commonly prescribed medication in the United States, with more than four million prescriptions.

Side effects

Common side effects with the inhaled form include respiratory infections, headaches, and throat inflammation. Serious side effects include an increased risk of infection, cataracts, Cushing's syndrome, and severe allergic reactions. Long-term use of the pill form may cause adrenal insufficiency. The pills may also cause mood or personality changes. The inhaled form is generally regarded as safe in pregnancy.

Occasionally, it may cause a cough upon inhalation. Deposition on the tongue and throat may promote oral candidiasis, which appears as a white coating, possibly with irritation. This may usually be prevented by rinsing the mouth with water after using the inhaler. Other adverse drug reaction side effects may rarely include: a smell similar to burning plastic, unpleasant taste, hoarseness or nasal congestion, pain or headache, and visual changes. Allergic reactions may occur, but rarely.

Nasal corticosteroids may be associated with central serous retinopathy.

Pharmacology
Beclometasone is mainly a glucocorticoid. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The activated glucocorticoid receptor-glucocorticoid complex up-regulates the expression of anti-inflammatory proteins in the nucleus (a process known as transactivation) and represses the expression of proinflammatory proteins in the cytosol by preventing the translocation of other transcription factors from the cytosol into the nucleus (transrepression).

Glucocorticoids are part of the feedback mechanism in the immune system which reduces certain aspects of immune function, such as inflammation.

Names 
Beclometasone dipropionate is the INN (International nonproprietary name) modified and beclomethasone dipropionate is the USAN and former BAN. It is a prodrug of the free form, beclometasone (INN). The prodrug beclometasone is marketed in Norway and Russia.

Clenil, Qvar are brandnames for the inhalers. Beconase, Alanase, Vancenase, Qnasl for the nasal spray or aerosol.

Ref: Wikipedia

4. Bilastine (in the tablet form) 

Bilastine (sold under the brand names BILLASI and Blexten, among others), is a second-generation antihistamine medication which is used in the treatment of allergic rhinoconjunctivitis and urticaria (hives).

It exerts its effect as a selective histamine H1 receptor antagonist, and has an effectiveness similar to cetirizine, fexofenadine, and desloratadine. It was developed in Spain by FAES Farma.

Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.

Bilastine has been effective in the treatment of diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and eye symptoms related to allergic rhinitis.

Side effects 

Toxicity of bilastine investigated in preclinical toxicology studies in mice, rats and dogs after oral and intravenous administration showed no mortality observed after oral administration of massive doses. After intravenous administration, LD50 (lethal dose for 50% of animals) values were 33 and 45–75 mg/kg in mice and rats, respectively. No signs of toxicity were observed in any organ after bilastine massive overdosing, either orally (in mice, rats and dogs), or intravenously (in rats and dogs) during 4 weeks. No effects on fertility, no teratogenic or mutagenic effects, and no apparent carcinogenic potential were seen in the studies carried out in rats, mice and rabbits.

In clinical research, bilastine has proven to be well tolerated, with an adverse events profile similar to that of placebo in healthy volunteers, patients with AR and with chronic idiopathic urticaria. Although the tolerance profile of bilastine and levocetirizine or desloratadine were very similar, bilastine was markedly better tolerated than cetirizine in a clinical assay in SAR, with fewer adverse events in the bilastine group. No anticholinergic adverse events were observed in the clinical trials with bilastine. No serious adverse events were reported during the research and there were no clinically significant changes in vital signs, electrocardiography (ECG) or laboratory tests. Pharmacokinetic/pharmacodynamic profiles and studies in special populations indicate that dose adjustment of bilastine is not necessary in elderly patients or in chronic liver disease or chronic kidney disease.

Ref: Wikipedia

5. Luliconazole Cream 

Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum and Epidermophyton floccosum.

Ref: Wikipedia

6. Adgain Plus Capsule 

- Facilitates protection of damaged hair

- Helps to counter premature greying of hair

- Helps to reduce the biotin deficiency

Adgain Plus Capsule helps in treating the hair loss due to changes in the hair structure because of stress.  The hair becomes thin, inelastic, brittle, lifeless, dull and colourless hair. Adgain plus capsules are a dietary supplement for hair. 

Key Ingredients:

- Biotin

- Calcium D-Pantothenate

- Iron

- Zinc

- Green Tea Powder

- L-Cysteine

- Thiamine

- Vitamin D3

- Yeast Extract

Key Benefits:

- It helps to protect the hair damaged by sunlight

- Reduces and protects the greying of the hair

- Improves the hair structure, strengthens the hair and increases the resistance of the hair from mechanical, chemical and sun damage

- Fortify the hair with the power of L- cystine, brewer's yeast and calcium pantothenate

- Works by treating or preventing the hair from biotin deficiency

- Adgain plus capsule is used for hair fall, retarded hair growth, damaged hair, and other conditions

Directions For Use: One tablet per day or as directed by the physician.

Ref: 1mg

Few tips for good hair health:

- Do not wash hair or scalp with hot water.

- Do not comb wet hair.

- Do not wear tight caps, hats, headwear, helmets, etc.

- Eat a lot of veg protein such as grams / chickpeas, sprouts, pulses. (Other rich protein sources could be cheese, nuts, soyabean, tofu, etc)

- Do not stress over little things. Avoid it as much as you can.

7. Keraglo Men Tablet 

Highlights:

- Helps to prevent hair fall and treat scalp problems

- Helps to improve the quality of hair and make them healthy

- Promotes healthy growth of hair and strengthen the hair

Keraglo Men Tablet contains gamma-linolenic acid, which is found mostly in plant-based oils such as barrage seed oil), multivitamins and multi-minerals. Gamma-Linolenic Acid is known to be an essential fatty acid that helps to stop hair loss as well as the growth of hair. 

Key Ingredients:
- Gamma-Linolenic acid
- Multivitamins
- Multi minerals

Key Benefits:
- It helps to normalize the hair growth cycle
- Enhances the quality of hair
- Helps to reduce hair fall

Directions For Use:
Keraglo Men Tablets are generally used by men who are suffering from hair loss. You can take 1 tablet daily with a glass of water, before or after a meal.

Safety Information:
- Read the instructions carefully before use
- Avoid contact with eyes, eyelid areas, nostril areas & close to the mouth
- Keep out of reach of the children
- Use under medical supervision

Ref: 1mg

8. D3 Sure Nano Shot Oral Solution 5ml 

MANUFACTURER: Aareen Healthcare Pvt Ltd
SALT COMPOSITION: Vitamin D3 (60000IU)

USES OF D3 SURE ORAL SOLUTION
- Vitamin D deficiency
- Osteoporosis

BENEFITS OF D3 SURE ORAL SOLUTION

- In Vitamin D deficiency
Normally your body creates vitamin D from sunlight, but you will be prescribed this medicine as a supplement if you do not have enough. It is important to keep taking it regularly to get the benefits. You may not notice it working but keep taking it in order to protect your bones. Additionally, it can boost your immunity and increase the body's resistance against various infections.

SIDE EFFECTS OF D3 SURE ORAL SOLUTION
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of 'D3 Sure': No common side effects seen

HOW D3 SURE ORAL SOLUTION WORKS
D3 Sure Nano Shot Oral Solution 5ml is a form of vitamin D. It raises vitamin D levels in your blood. This in turn raises calcium levels in your blood by helping you absorb more calcium from food.

Ref: 1mg