Para 1: Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea) caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum and Epidermophyton floccosum. Trade names: Luzu, Luzarn, Lulicon, LULY, Zyluli, Luris Ref: Luliconazole Para 2: Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under the brand name Luzu. Luliconazole is also approved in Japan. Ref: Luliconazole National Library of Medicine (National Center for Biotechnology Information) Para 3: An in vivo study in adult subjects with moderate to severe interdigital tinea pedis and tinea cruris (jock itch) showed that LUZU Cream, 1% is mostly a weak inhibitor of CYP2C19. In a separate trial in adolescent subjects with tinea cruris, in vivo blood levels of LUZU Cream, 1%, were seen to approach those levels sufficient to show moderate inhibition of CYP2C19. Ref: Luzu drug Brands 1. Dexoderm-L (20g) From: Micro Labs Salt: Luliconazole Cream 1% w/w Preservative: Benzyl Alcohol 1% w/w 2. Lulifin Cream (20g) Prescription Required Manufacturer: Sun Pharmaceutical Industries Ltd SALT COMPOSITION: Luliconazole (1% w/w) Preservative: 2.1. Methylparaben Methylparaben is an anti-fungal agent often used in a variety of cosmetics and personal-care products. It is also used as a food preservative and has the E number E218. Methylparaben is commonly used as a fungicide in Drosophila food media at 0.1%. Methylparaben, also methyl paraben, one of the parabens, is a preservative with the chemical formula CH₃. It is the methyl ester of p-hydroxybenzoic acid. 2.2. Benzyl alcohol Benzyl alcohol is an aromatic alcohol with the formula C₆H₅CH₂OH. The benzyl group is often abbreviated "Bn", thus benzyl alcohol is denoted as BnOH. Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor. It is a useful solvent due to its polarity, low toxicity, and low vapor pressure.
Tuesday, March 16, 2021
Luliconazole
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment